Progesterone’s role in frozen embryo transfers

Progesterone is currently administered by vaginal gels, creams or inserts or with injections into a muscle. These methods can be painful, messy and stressful. Carolina Conceptions is currently recruiting patients for a clinical trial sponsored by IBSA Group that is researching easier ways to administer the hormone progesterone, which plays a vital role in pregnancy and frozen embryo transfers (FET).

Eligible subjects will have their frozen #embryo transfer (FET) cycle covered.

Who is eligible to help us make progress?

  • Women ages 35-42.
  • Have regular menstrual cycles (24-38 days).
  • Are planning a single embryo transfer.
  • Have completed a normal uterine cavity evaluation, such as hysteroscopy, hysterosalpingogram, or SIS, within the past year.
  • Have a normal pap smear.

 Eligible participants who join the study will:

  • Attend scheduled clinic visits.
  • Have blood drawn to evaluate hormone levels.
  • Complete transvaginal ultrasounds designed to monitor changes to the ovaries, uterine lining or pregnancy, if applicable.
  • Receive study medications to self-administer as instructed by the clinic staff.

For a complete list of eligibility criteria, visit NCT04549116 or visit for more information.