Some couples facing this news decide to pursue less aggressive treatment like intrauterine insemination (IUI) and hope for the best, while others choose to take a more aggressive approach like IVF. Because IVF is a highly controlled process, it often helps uncover very subtle obstacles to conception for couples facing unexplained infertility. Meanwhile, the fertilization techniques (ICSI) and ability to develop multiple embryos simultaneously will provide a significant improvement of pregnancy over other treatments for unexplained infertility.
Once a diagnosis of unexplained infertility is determined, the chance of spontaneous pregnancy each month is approximately 2%. Without a clear cause of infertility, a spontaneous pregnancy is still possible though the chance is very low. IUI has pregnancy rates that range between 12 and 20%, while IVF has pregnancy rates of >70%, depending on the age of the female.
Your physician will help you consider your options so you can make an informed decision for how to move forward.